Investigation of Adenosine Precursors and Biologically Active Peptides in Cultured Fresh Mycelium of Wild Medicinal Mushrooms

Adenosine, known as an endogenous neuroprotective agent and acting a cytoprotective modulator in organisms, is the subject of considerable scientific interest. Medicinal mushrooms represent good source bioactive compounds due to their composition potent adaptogenic action, affecting more than 300 biochemical processes functions organisms. The aim present study was investigate adenosine precursors biologically active peptides cultured fresh mycelium with focus on Ganoderma lucidum (Reishi) Cordyceps sinensis best studied species. Biologically extracts are derived by fermentation Bacillus subtilis NBIMCC 2353 strain. Enhancement total proteolytic activity culture medium enriched native bovine collagen protein recorded. results demonstrate clear trend increasing cordycepin content militaris sample grown optimized composition, presence being 2.22% 0.64%. obtained increase 1.9% for 0.24% adenosine, respectively. application combined biotechnological approaches use components from natural organic sources resulting final product high biological determine relevant significant its practical application.